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FLNA Antibody

CAT: 0223-63-193Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-193Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.
NCBI Gene ID
2316
Swiss Prot
P21333
Accession Number
P21333
Host
Rabbit
Reactivity
Human
Immunogen
This FLNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1025-1054 amino acids from human FLNA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
281 kDa
Fragment
Rabbit Ig
Symbol
FLNA
NCBI Official Name
Filamin-A
NCBI Organism
Homo sapiens
Background Reference 01
Ravid, D., Exp. Cell Res. 314 (15), 2762-2773 (2008)
Background Reference 02
Maceyka, M., Mol. Cell. Biol. 28 (18), 5687-5697 (2008)
Other Product Names
Filamin-A, FLN-A, Actin-binding protein 280, ABP-280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, Non-muscle filamin, FLNA, FLN, FLN1
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
116241365
Physical Properties
Liquid

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