FLNC Antibody

CAT: 0223-14-747Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-14-747Size:100 µL
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Background
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2318
Swiss Prot
Q14315
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 2160-2340 of human FLNC (NP_001449.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
Affinity purification
Positive Control
A-549
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 302kDa
Fragment
IgG
Symbol
FLNC
Positive Control 2
LO2
Positive Control 3
NIH/3T3
NCBI Official Name
Filamin C
NCBI Organism
Homo sapiens
Other Product Names
ABP-28ABP280A, ABPA, ABPL, CMH26, FLN2, MFM5, MPD4, RCM5, filamin-C, ABP-280-like protein, ABP-L, gamma filamin, actin binding protein 28filamin C, gamma, filamin-2, gamma filamin
Tested Applications
WB, IF
Physical Properties
Liquid

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