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PDGFRB Antibody

CAT: 0223-63-122Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-122Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides.
NCBI Gene ID
5159
Swiss Prot
P09619
Accession Number
P09619
Host
Rabbit
Reactivity
Human
Immunogen
This PDGFRB antibody is generated from rabbits immunized with human recombinant PDGFRB protein.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
124 kDa
Fragment
Rabbit Ig
Symbol
PDGFRB
NCBI Official Name
Platelet-derived growth factor receptor beta
NCBI Organism
Homo sapiens
Background Reference 01
Wu, H., et al., J. Biol. Chem. 278 (42) :40425-40428 (2003) .
Background Reference 02
Whiteman, E.L., et al., Endocrinology 144 (9) :3811-3820 (2003) .
Background Reference 03
Uren, A., et al., Oncogene 22 (15) :2334-2342 (2003) .
Background Reference 04
Steer, E.J., et al., Acta Haematol. 107 (2) :113-122 (2002) .
Other Product Names
Platelet-derived growth factor receptor beta, PDGF-R-beta, PDGFR-beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1
Tested Applications
WB, IHC-P, IF
Protein ID
129890
Physical Properties
Liquid

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