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PDGFRL Antibody

CAT: 0223-59-183Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-183Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
NCBI Gene ID
5157
Swiss Prot
Q15198
Accession Number
Q15198
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-44 amino acids from the N-terminal region of human PDGFRL.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PDGFRL
NCBI Official Name
Platelet-derived growth factor receptor-like protein
NCBI Organism
Homo sapiens
Background Reference 01
Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)
Background Reference 02
Guo, F.J., et al. World J. Gastroenterol. 16 (12) :1465-1472 (2010)
Background Reference 03
Riker, A.I., et al. BMC Med Genomics 1, 13 (2008) :
Background Reference 04
Xu, M., et al. BMC GenomicsSUPPL 1, S12 (2008) :
Other Product Names
Platelet-derived growth factor receptor-like protein, PDGFR-like protein, PDGF receptor beta-like tumor suppressor, PDGFRL, PRLTS
Tested Applications
WB
Protein ID
74762141
Physical Properties
Liquid

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