Products for Research Use Only
RegisterLogin

FGFR2 Antibody

CAT: 0223-63-087Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-63-087Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
FGFR2 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in FGFR2 gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis.
NCBI Gene ID
2263
Swiss Prot
P21802
Accession Number
P21802
Host
Rabbit
Reactivity
Human
Immunogen
This FGFR2 antibody is generated from rabbits immunized with a his tag recombinant protein of human FGFR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
92 kDa
Fragment
Rabbit Ig
Symbol
FGFR2
NCBI Official Name
Fibroblast growth factor receptor 2
NCBI Organism
Homo sapiens
Background Reference 01
Park W.-J., Meyers G.A., Li X.Hum. Mol. Genet. 4:1229-1233 (1995)
Background Reference 02
Lajeunie E., Wei M.H., Bonaventure J.Nat. Genet. 9:108-108 (1995)
Background Reference 03
Rutland P., Pulleyn L.J., Reardon W., Baraister M.Nat. Genet. 9:173-176 (1995)
Background Reference 04
McGillivray G., Savarirayan R., Cox T.C.J. Med. Genet. 42:656-662 (2005)
Other Product Names
Fibroblast growth factor receptor 2, FGFR-2, K-sam, KGFR, Keratinocyte growth factor receptor, CD332, FGFR2, BEK, KGFR, KSAM
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
120049
Physical Properties
Liquid

Related Products

CatalogName
42-748PFGFR2 Peptide
10-861Bemarituzumab (FGFR2) - Research Grade Biosimilar
10-794Aprutumab (FGFR2) - Research Grade Biosimilar
79-709FGFR4 Antibody
63-084FGFR1 Antibody
7425-01FGFR3 Antibody
7425-002mgFGFR3 Antibody
63-088FGFR4 Antibody
63-080FGFR1 Antibody
63-083FGFR1 Antibody

Alternative Products

CatalogName
70R-49743FGFR2 antibody

Popular Products