EphB4 Antibody

CAT: 0223-63-061Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-63-061Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.
NCBI Gene ID
2050
Swiss Prot
P54760
Accession Number
P54760
Host
Rabbit
Reactivity
Human
Immunogen
This EphB4 antibody is generated from rabbits immunized with human recombinant EphB4 protein.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Symbol
EPHB4
NCBI Official Name
Ephrin type-B receptor 4
NCBI Organism
Homo sapiens
Background Reference 01
Steinle, J.J., et al., J. Biol. Chem. 277 (46) :43830-43835 (2002) . Suenobu, S., et al., Biochem. Biophys. Res. Commun. 293 (3) :1124-1131 (2002) . Wang, Z., et al., Blood 99 (8) :2740-2747 (2002) . Wilson, M.D., et al., Nucleic Acids Res. 29 (6) :1352-1365 (2001) . Wilkinson, D.G., Nat Rev Neurosci 2 (3) :155-164 (2001) .
Other Product Names
Ephrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11, EPHB4, HTK, MYK1, TYRO11
Tested Applications
WB, IHC-P
Protein ID
19860819
Physical Properties
Liquid

Related Products

CatalogName
45-546PEPHB4 Peptide
96-266EPHB4 Recombinant Protein
23-522EPHA4 Antibody
63-059EphB3 Antibody
48-176EPHA4 Antibody
63-042EphA4 Antibody
63-043EphA4 Antibody
63-054EphB1 Antibody
63-060EphB3 Antibody
63-064EphB6 Antibody

Alternative Products

CatalogName
MBS8593877-01EPHB4 Antibody

Popular Products