ACO2 Antibody

• Background:

  ACO2 belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

• NCBI Gene ID:

  50

• Swiss Prot:

  Q99798

• Accession Number:

  Q99798

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ACO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-325 amino acids from the Central region of human ACO2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  85 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ACO2

• NCBI Official Name:

  Aconitate hydratase, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yu, Z., Prostate 66 (10), 1061-1069 (2006)

• Background Reference 02:

  Tsui, K.H., Asian J. Androl. (3), 307-315 (2006)

• Background Reference 03:

  Ahmed, M., J. Proteome Res. (3), 931-940 (2005)

• Other Product Names:

  Aconitate hydratase, mitochondrial, Aconitase, Citrate hydro-lyase, ACO2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  6686275

• Physical Properties:

  Liquid