PPBP Antibody

• Background:

  PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.

• NCBI Gene ID:

  5473

• Swiss Prot:

  P02775

• Accession Number:

  P02775

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human PPBP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  14 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  PPBP

• NCBI Official Name:

  Platelet basic protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Majumdar S., J. Biol. Chem. 266:5785-5789 (1991)

• Background Reference 02:

  Zhang C., Blood 98:610-617 (2001)

• Background Reference 03:

  Aivado, M., Proc. Natl. Acad. Sci. U.S.A. 104 (4), 1307-1312 (2007)

• Other Product Names:

  Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, Connective tissue-activating peptide III, CTAP-III, LA-PF4, Low-affinity platelet factor IV, TC-2, Connective tissue-activating peptide III (1-81), CTAP-III (1-81), Beta-thromboglobulin, Beta-TG, Neutrophil-activating peptide 2 (74), NAP-2 (74), Neutrophil-activating peptide 2 (73), NAP-2 (73), Neutrophil-activating peptide 2, NAP-2, TC-1, Neutrophil-activating peptide 2 (1-66), NAP-2 (1-66), Neutrophil-activating peptide 2 (1-63), NAP-2 (1-63), PPBP, CTAP3, CXCL7, SCYB7, TGB1, THBGB1

• Tested Applications:

  WB

• Protein ID:

  129874

• Physical Properties:

  Liquid