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CAMK2A Antibody

CAT: 0223-62-898Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-898Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca (2+) /calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM) -dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.
NCBI Gene ID
815
Swiss Prot
Q9UQM7
Accession Number
Q9UQM7
Host
Rabbit
Reactivity
Human
Immunogen
This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-371 amino acids from the C-terminal region of human CAMK2A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
CAMK2A
NCBI Official Name
Calcium/calmodulin-dependent protein kinase type II subunit alpha
NCBI Organism
Homo sapiens
Background Reference 01
Lee, C.W., Mol. Pharmacol. 73 (5), 1454-1464 (2008)
Background Reference 02
Yuan, K., Lab. Invest. 87 (9), 938-950 (2007)
Other Product Names
Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968
Tested Applications
WB, IHC-P
Protein ID
296434552
Physical Properties
Liquid

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