CAMK2D Antibody

• Background:

  CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.

• NCBI Gene ID:

  817

• Swiss Prot:

  Q13557

• Accession Number:

  Q13557

• Host:

  Rabbit

• Reactivity:

  Human, Monkey

• Immunogen:

  This CAMK2D (CAMK2 delta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CAMK2D (CAMK2 delta) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CAMK2D

• NCBI Official Name:

  Calcium/calmodulin-dependent protein kinase type II subunit delta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rochlitz, H., et al., Diabetologia 43 (4) :465-473 (2000) .

• Background Reference 02:

  Hoch, B., et al., Circ. Res. 84 (6) :713-721 (1999) .

• Background Reference 03:

  Tombes, R.M., et al., Biochim. Biophys. Acta 1355 (3) :281-292 (1997) .

• Other Product Names:

  Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II subunit delta, CaMK-II subunit delta, CAMK2D, CAMKD

• Tested Applications:

  WB, IHC-P

• Protein ID:

  116242602

• Physical Properties:

  Liquid