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CAMK2D Antibody

CAT: 0223-62-734Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-734Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Expression of CAMK2 delta is significantly increased in patients suffering from dilated cardiomyopathy.
NCBI Gene ID
817
Swiss Prot
Q13557
Accession Number
Q13557
Host
Rabbit
Reactivity
Human, Monkey
Immunogen
This CAMK2D (CAMK2 delta) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 448-478 amino acids from the C-terminal region of human CAMK2D (CAMK2 delta) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Symbol
CAMK2D
NCBI Official Name
Calcium/calmodulin-dependent protein kinase type II subunit delta
NCBI Organism
Homo sapiens
Background Reference 01
Rochlitz, H., et al., Diabetologia 43 (4) :465-473 (2000) .
Background Reference 02
Hoch, B., et al., Circ. Res. 84 (6) :713-721 (1999) .
Background Reference 03
Tombes, R.M., et al., Biochim. Biophys. Acta 1355 (3) :281-292 (1997) .
Other Product Names
Calcium/calmodulin-dependent protein kinase type II subunit delta, CaM kinase II subunit delta, CaMK-II subunit delta, CAMK2D, CAMKD
Tested Applications
WB, IHC-P
Protein ID
116242602
Physical Properties
Liquid

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