CAMKK2 Antibody

CAT: 0223-62-672Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-672Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca (2+) /calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1.
NCBI Gene ID
10645
Swiss Prot
Q96RR4
Accession Number
Q96RR4
Host
Rabbit
Reactivity
Human
Immunogen
This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human CAMKK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Symbol
CAMKK2
NCBI Official Name
Calcium/calmodulin-dependent protein kinase kinase 2
NCBI Organism
Homo sapiens
Background Reference 01
Hsu, L.S., et al., J. Biol. Chem. 276 (33) :31113-31123 (2001) .
Background Reference 02
Hsu, L.S., et al., J. Biomed. Sci. 5 (2) :141-149 (1998) .
Background Reference 03
Anderson, K.A., et al., J. Biol. Chem. 273 (48) :31880-31889 (1998) .
Background Reference 04
Ishikawa, Y., et al., FEBS Lett. 550 (1-3), 57-63 (2003)
Other Product Names
Calcium/calmodulin-dependent protein kinase kinase 2, CaM-KK 2, CaM-kinase kinase 2, CaMKK 2, Calcium/calmodulin-dependent protein kinase kinase beta, CaM-KK beta, CaM-kinase kinase beta, CaMKK beta, CAMKK2, CAMKKB, KIAA0787
Tested Applications
WB, IHC-P
Protein ID
317373374
Physical Properties
Liquid

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