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GIT1 Antibody

CAT: 0223-62-895Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-895Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GIT1 is a GTPase-activating protein for the ADP ribosylation factor family. It may serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. It increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia.
NCBI Gene ID
28964
Swiss Prot
Q9Y2X7
Accession Number
Q9Y2X7
Host
Rabbit
Reactivity
Human
Immunogen
This GIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-517 amino acids from human GIT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Symbol
GIT1
NCBI Official Name
ARF GTPase-activating protein GIT1
NCBI Organism
Homo sapiens
Background Reference 01
Sato, H., Biochem. Biophys. Res. Commun. 368 (1), 157-161 (2008)
Background Reference 02
Jones, N.P., Mol. Cell. Biol. 27 (16), 5790-5805 (2007)
Background Reference 03
Schmalzigaug, R., Cell. Signal. 19 (8), 1733-1744 (2007)
Background Reference 04
Stockton, R., Mol. Biol. Cell 18 (6), 2346-2355 (2007)
Other Product Names
ARF GTPase-activating protein GIT1, ARF GAP GIT1, Cool-associated and tyrosine-phosphorylated protein 1, CAT-1, CAT1, G protein-coupled receptor kinase-interactor 1, GRK-interacting protein 1, GIT1
Tested Applications
WB, IHC-P
Protein ID
45645212
Physical Properties
Liquid

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