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MYCN Antibody

CAT: 0223-62-879Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-879Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.
NCBI Gene ID
4613
Swiss Prot
P04198
Accession Number
P04198
Host
Rabbit
Reactivity
Human
Immunogen
This MYCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human MYCN.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MYCN
NCBI Official Name
N-myc proto-oncogene protein
NCBI Organism
Homo sapiens
Background Reference 01
Combaret, V., Pediatr Blood Cancer 53 (3), 329-331 (2009)
Background Reference 02
Alvarez-Rodriguez, R., J. Cell. Sci. 122 (PT 5), 595-599 (2009)
Background Reference 03
Jacobs, J.F., BMC Cancer 9, 239 (2009)
Other Product Names
N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, bHLHe37, MYCN, BHLHE37, NMYC
Tested Applications
WB
Protein ID
127604
Physical Properties
Liquid

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