MYC Antibody

• Background :

  C-myc, v-myc myelocytomatosis viral oncogene homolog. This protein participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence CAC[GA]TG. Seems to activate the transcription of growth-related genes.

• NCBI Gene ID :

  4609

• Swiss Prot :

  P01106

• Accession Number :

  NP_002458.1

• Host :

  Chicken

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  268-386

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  Antigen affinity-purified

• Concentration :

  1 mg/mL

• Buffer :

  Phosphate-Buffered Saline. No preservatives added.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  MYC antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  48.8 kDa (calculated)

• Applications Notes :

  C-myc (N-88) antibody can be used for the detection of C-myc (N-88) by Western blot, may also work for IHC and ICC.

• Symbol :

  MYC

• NCBI Official Name :

  V-myc avian myelocytomatosis viral oncogene homolog

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Adams, J. M., Gerondakis, S., Webb, E., Corcoran, L. M., Cory, S. Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas. Proc. Nat. Acad. Sci. 80: 1982-1986, 1983.

• Other Product Names :

  BHLHE39, Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, MRTL, MYCC, c-Myc, Cmyc (N88)

• Tested Applications :

  WB

• Protein ID :

  12962935

• Physical Properties :

  Liquid