Products for Research Use Only

Aurora-B Antibody

CAT: 0223-62-751Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-751Size:400 µL
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Background
Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. STK12 (Aurora kinase B) localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A localizes to centrosomes
NCBI Gene ID
9212
Swiss Prot
Q96GD4
Accession Number
Q96GD4
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Aurora-B (ARK/STK12) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-313 amino acids from the Central region of human Aurora-B (ARK/STK12) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
AURKB
NCBI Official Name
Aurora kinase B
NCBI Organism
Homo sapiens
Background Reference 01
Kimura, M., et al., Biochem. Biophys. Res. Commun. 316 (3) :930-936 (2004) .
Background Reference 02
Yasui, Y., et al., J. Biol. Chem. 279 (13) :12997-13003 (2004) .
Background Reference 03
Lampson, M.A., et al., Nat. Cell Biol. 6 (3) :232-237 (2004) .
Background Reference 04
Wheatley, S.P., et al., J. Biol. Chem. 279 (7) :5655-5660 (2004) .
Other Product Names
Aurora kinase B, Aurora 1, Aurora- and IPL1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, ARK-2, Aurora-related kinase 2, STK-1, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 5, Serine/threonine-protein kinase aurora-B, AURKB, AIK2, AIM1, AIRK2, ARK2, STK1, STK12, STK5
Tested Applications
WB, IHC-P
Protein ID
317373473
Physical Properties
Liquid