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SCYL1 Antibody

CAT: 0223-62-735Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-735Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SCYL1 forms multimers following transfection into COS-7 cells. SCYL1 forms a 300-kD trimer using crosslinking reagents. Biochemical analysis revealed no phosphorylation or autophosphorylation activity.The 707-amino acid SCYL1 variant, variant 2, localized to centrosomes during mitosis. During interphase, fluorescence-tagged variant 2 localized in the cytoplasm as well as centrosomes. However, at the beginning of mitosis, the fluorescence appeared as a pair of bright nuclear foci that followed centrosome localization throughout mitosis, while maintaining diffuse cytoplasmic labeling. Endogenous variant 2 in HeLa cells showed a similar staining pattern. Centrosomal localization was independent of microtubules.
NCBI Gene ID
57410
Swiss Prot
Q96KG9
Accession Number
Q96KG9
Host
Rabbit
Reactivity
Human
Immunogen
This SCYL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the N-terminal region of human SCYL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
90 kDa
Fragment
Rabbit Ig
Symbol
SCYL1
NCBI Official Name
N-terminal kinase-like protein
NCBI Organism
Homo sapiens
Background Reference 01
Tang, Z., et al., Biochem. Biophys. Res. Commun. 324 (4) :1324-1332 (2004) .
Background Reference 02
Kato, M., et al., Genomics 79 (6) :760-767 (2002) .
Background Reference 03
Liu, S.C., et al., Biochim. Biophys. Acta 1517 (1) :148-152 (2000) .
Background Reference 04
Van Asseldonk, M., et al., Genomics 66 (1) :35-42 (2000) .
Other Product Names
N-terminal kinase-like protein, Coated vesicle-associated kinase of 90 kDa, SCY1-like protein 1, Telomerase regulation-associated protein, Telomerase transcriptional element-interacting factor, Teratoma-associated tyrosine kinase, SCYL1, CVAK90, GKLP, NTKL, TAPK, TEIF, TRAP
Tested Applications
WB, IHC-P
Protein ID
74762671
Physical Properties
Liquid

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