PANK1 Antibody

• Background :

  PANK1 belongs to the pantothenate kinase family. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by CoA.

• NCBI Gene ID :

  53354

• Swiss Prot :

  Q8TE04

• Accession Number :

  Q8TE04

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This PANK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 amino acids from the N-terminal region of human PANK1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  64 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  PANK1

• NCBI Official Name :

  Pantothenate kinase 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ramaswamy, G., et al., J. Lipid Res. 45 (1) :17-31 (2004) .

• Background Reference 02 :

  Ni, X., et al., Int. J. Biochem. Cell Biol. 34 (2) :109-115 (2002) .

• Background Reference 03 :

  Zhou, B., et al., Nat. Genet. 28 (4) :345-349 (2001) .

• Background Reference 04 :

  Westaway, S.K., et al., Int. J. Biochem. Cell Biol. 34 (12), 1629 (2002) () : () .

• Other Product Names :

  Pantothenate kinase 1, hPanK, hPanK1, Pantothenic acid kinase 1, PANK1, PANK

• Tested Applications :

  WB

• Protein ID :

  27805665

• Physical Properties :

  Liquid