CAMK2A Antibody

• Background :

  CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.

• NCBI Gene ID :

  815

• Swiss Prot :

  Q9UQM7

• Accession Number :

  Q9UQM7

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CAMK2A (CAMK2 alpha) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-478 amino acids from the C-terminal region of human CAMK2A (CAMK2 alpha) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification :

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  54 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CAMK2A

• NCBI Official Name :

  Calcium/calmodulin-dependent protein kinase type II subunit alpha

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Blume-Jensen P, et al. Nature 2001. 411: 355.

• Background Reference 02 :

  Cantrell D, J. Cell Sci. 2001. 114: 1439.

• Background Reference 03 :

  JhiangOncogene 2000. 19: 5590.

• Background Reference 04 :

  Manning G, et al. Science 2002. 298: 1912.

• Other Product Names :

  Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968

• Tested Applications :

  WB, IHC-P

• Protein ID :

  296434552

• Physical Properties :

  Liquid