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CAMK2A Antibody

CAT: 0223-62-732Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-732Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
NCBI Gene ID
815
Swiss Prot
Q9UQM7
Accession Number
Q9UQM7
Host
Rabbit
Reactivity
Human
Immunogen
This CAMK2A (CAMK2 alpha) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-478 amino acids from the C-terminal region of human CAMK2A (CAMK2 alpha) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Symbol
CAMK2A
NCBI Official Name
Calcium/calmodulin-dependent protein kinase type II subunit alpha
NCBI Organism
Homo sapiens
Background Reference 01
Blume-Jensen P, et al. Nature 2001. 411: 355.
Background Reference 02
Cantrell D, J. Cell Sci. 2001. 114: 1439.
Background Reference 03
JhiangOncogene 2000. 19: 5590.
Background Reference 04
Manning G, et al. Science 2002. 298: 1912.
Other Product Names
Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968
Tested Applications
WB, IHC-P
Protein ID
296434552
Physical Properties
Liquid

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