AMHR2 Antibody

CAT: 0223-62-666Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-666Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The AMH receptor (AMHR or AMHR2) is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes.
NCBI Gene ID
269
Swiss Prot
Q16671
Accession Number
Q16671
Host
Rabbit
Reactivity
Human
Immunogen
This AMHR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human AMHR2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
63 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AMHR2
NCBI Official Name
Anti-Muellerian hormone type-2 receptor
NCBI Organism
Homo sapiens
Background Reference 01
Picard, J.Y., et al., J. Soc. Biol. 196 (3) :217-221 (2002) . Teixeira, J., et al., Endocr. Rev. 22 (5) :657-674 (2001) . Imbeaud, S., et al., Nat. Genet. 11 (4) :382-388 (1995) . Visser, J.A., et al., Biochem. Biophys. Res. Commun. 215 (3) :1029-1036 (1995) . Sinisi, A.A., et al., J. Endocrinol. Invest. 26 (3 Suppl), 23-28 (2003) .
Other Product Names
Anti-Muellerian hormone type-2 receptor, Anti-Muellerian hormone type II receptor, AMH type II receptor, MIS type II receptor, MISRII, MRII, AMHR2, AMHR, MISR2
Tested Applications
WB
Protein ID
9087133
Physical Properties
Liquid

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