NEK8 Antibody

• Background:

  NEK8 is a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans.

• NCBI Gene ID:

  284086

• Swiss Prot:

  Q86SG6

• Accession Number:

  Q86SG6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NEK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-95 amino acids from the N-terminal region of human NEK8.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  75 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NEK8

• NCBI Official Name:

  Serine/threonine-protein kinase Nek8

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Valkova, N. et al. Mol. Cell Proteomics (7), 1009-1018 (2005)

• Background Reference 02:

  Bowers, A.J. et al. Gene 328, 135-142 (2004)

• Background Reference 03:

  Holland, P.M. et al. J. Biol. Chem. 277 (18), 16229-16240 (2002)

• Other Product Names:

  Serine/threonine-protein kinase Nek8, Never in mitosis A-related kinase 8, NimA-related protein kinase 8, Nima-related protein kinase 12a, NEK8, JCK, NEK12A

• Tested Applications:

  WB

• Protein ID:

  34098463

• Physical Properties:

  Liquid