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NEK3 Antibody

CAT: 0223-63-381Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-381Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. NEK3 is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm.
NCBI Gene ID
4752
Swiss Prot
P51956
Accession Number
P51956
Host
Rabbit
Reactivity
Human
Immunogen
This NEK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-361 amino acids from the Central region of human NEK3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
58 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:2000
Symbol
NEK3
NCBI Official Name
Serine/threonine-protein kinase Nek3
NCBI Organism
Homo sapiens
Background Reference 01
Schultz, S.J., et al., Cell Growth Differ. 5 (6) :625-635 (1994) .
Background Reference 02
Schultz, S.J., et al., Cell Growth Differ. 4 (10) :821-830 (1993) .
Background Reference 03
Kimura, M., et al., Cytogenet. Cell Genet. 95 (3-4), 177-182 (2001) .
Other Product Names
Serine/threonine-protein kinase Nek3, HSPK 36, Never in mitosis A-related kinase 3, NimA-related protein kinase 3, NEK3
Tested Applications
WB
Protein ID
20178297
Physical Properties
Liquid

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