SERPINC1 Antibody

• Background:

  SERPINC1 is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin.

• NCBI Gene ID:

  462

• Swiss Prot:

  P01008

• Accession Number:

  P01008

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This SERPINC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human SERPINC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  53 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SERPINC1

• NCBI Official Name:

  Antithrombin-III

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Doi, T., Arch. Biochem. Biophys. 489 (1-2), 62-67 (2009)

• Background Reference 02:

  Sun, X.J., J. Biol. Chem. 264 (19), 11288-11293 (1989)

• Other Product Names:

  Antithrombin-III, ATIII, Serpin C1, SERPINC1, AT3

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  113936

• Physical Properties:

  Liquid