SERPINE1 Antibody

• Background:

  This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  5054

• Swiss Prot:

  P05121

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 24-158 of human SERPINE1 (NP_000593.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HT-1080

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 45kDa

• Fragment:

  IgG

• Symbol:

  SERPINE1

• Positive Control 2:

  SH-SY5Y

• Positive Control 3:

  Mouse liver

• Positive Control 4:

  Rat liver

• NCBI Official Name:

  Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  SERPINE1, PAI, PAI-1, PAI1, PLANH1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid