SERPING1 Antibody

• Background:

  SERPING1 is a highly glycosylated plasma protein involved in the regulation of the complement cascade. This protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE) .

• NCBI Gene ID:

  710

• Swiss Prot:

  P05155

• Accession Number:

  P05155

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SERPING1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the Central region of human SERPING1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SERPING1

• NCBI Official Name:

  Plasma protease C1 inhibitor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Park, K.H., Mol. Vis. 15, 200-207 (2009)

• Background Reference 02:

  Gosswein, T., Cytogenet. Genome Res. 121 (3-4), 181-188 (2008)

• Other Product Names:

  Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1, SERPING1, C1IN, C1NH

• Tested Applications:

  WB, IHC-P, IF

• Protein ID:

  124096

• Physical Properties:

  Liquid