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SERPINE1 Antibody

CAT: 0223-56-733Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-733Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
5054
Swiss Prot
P05121
Accession Number
P05121
Host
Rabbit
Reactivity
Human
Immunogen
This SERPINE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human SERPINE1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
SERPINE1
NCBI Official Name
Plasminogen activator inhibitor 1
NCBI Organism
Homo sapiens
Background Reference 01
Ma, Z., et al. Biochem. Biophys. Res. Commun. 400 (4) :569-574 (2010)
Background Reference 02
Ince, D.A., et al. Genet Test Mol Biomarkers 14 (5) :643-647 (2010)
Background Reference 03
Bern, M.M., et al. Clin. Appl. Thromb. Hemost. 16 (5) :574-578 (2010)
Background Reference 04
Markl, B., et al.Surg Oncol 102 (3) :235-241 (2010)
Other Product Names
Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PAI1, PLANH1
Tested Applications
WB, Flow
Protein ID
129576
Physical Properties
Liquid

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