TIMP1 Antibody

CAT: 0223-62-416Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-416Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TIMP1 belongs to the TIMP family. The proteins in this family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.
NCBI Gene ID
7076
Swiss Prot
P01033
Accession Number
P01033
Host
Rabbit
Reactivity
Human
Immunogen
This TIMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TIMP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Symbol
TIMP1
NCBI Official Name
Metalloproteinase inhibitor 1
NCBI Organism
Homo sapiens
Background Reference 01
Safranek, J., Anticancer Res. 29 (7), 2513-2517 (2009) Onal, I.K., Eur. J. Intern. Med. 20 (4), 369-372 (2009) Okamura, H., Int. J. Oncol. 35 (1), 181-186 (2009)
Other Product Names
Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
135850
Physical Properties
Liquid

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