TIMP1 Antibody

• Background:

  TIMP1 belongs to the TIMP family. The proteins in this family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.

• NCBI Gene ID:

  7076

• Swiss Prot:

  P01033

• Accession Number:

  P01033

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TIMP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human TIMP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TIMP1

• NCBI Official Name:

  Metalloproteinase inhibitor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Safranek, J., Anticancer Res. 29 (7), 2513-2517 (2009) Onal, I.K., Eur. J. Intern. Med. 20 (4), 369-372 (2009) Okamura, H., Int. J. Oncol. 35 (1), 181-186 (2009)

• Other Product Names:

  Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  135850

• Physical Properties:

  Liquid