TIMP4 Antibody

• Background:

  This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

• NCBI Gene ID:

  7079

• Swiss Prot:

  Q99727

• Accession Number:

  Q99727

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human TIMP4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TIMP4

• NCBI Official Name:

  Metalloproteinase inhibitor 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nalpas, B., et al. Gut 59 (8) :1120-1126 (2010)

• Background Reference 02:

  Bailey, S.D., et al. Diabetes Care (2010) In press :

• Background Reference 03:

  Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press :

• Background Reference 04:

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Other Product Names:

  Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4, TIMP4

• Tested Applications:

  WB, IHC-P

• Protein ID:

  3915135

• Physical Properties:

  Liquid