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TIMP4 Antibody

CAT: 0223-55-060Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-55-060Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
NCBI Gene ID
7079
Swiss Prot
Q99727
Accession Number
Q99727
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human TIMP4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
26 kDa
Fragment
Rabbit Ig
Symbol
TIMP4
NCBI Official Name
Metalloproteinase inhibitor 4
NCBI Organism
Homo sapiens
Background Reference 01
Nalpas, B., et al. Gut 59 (8) :1120-1126 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 03
Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press :
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4, TIMP4
Tested Applications
WB, IHC-P
Protein ID
3915135
Physical Properties
Liquid

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