RRM2 Antibody

• Background:

  RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.

• NCBI Gene ID:

  6241

• Swiss Prot:

  P31350

• Accession Number:

  P31350

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RRM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human RRM2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RRM2

• NCBI Official Name:

  Ribonucleoside-diphosphate reductase subunit M2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kolesar, J., Cancer Chemother. Pharmacol. 64 (1), 79-86 (2009)

• Background Reference 02:

  Liu, X., Methods Mol. Biol. 477, 195-206 (2008)

• Other Product Names:

  Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit, RRM2, RR2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  400979

• Physical Properties:

  Liquid