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IL1R Antibody

CAT: 0223-62-259Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-259Size:400 µL
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Background
IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9) . Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
NCBI Gene ID
3554
Swiss Prot
P14778
Accession Number
P14778
Host
Rabbit
Reactivity
Human
Immunogen
This IL1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human IL1R.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Symbol
IL1R1
NCBI Official Name
Interleukin-1 receptor type 1
NCBI Organism
Homo sapiens
Background Reference 01
Debets, R., et al., J. Immunol. 167 (3) :1440-1446 (2001) .
Background Reference 02
Dale, M., et al., Genomics 57 (1) :177-179 (1999) .
Background Reference 03
Torigoe, K., et al., J. Biol. Chem. 272 (41) :25737-25742 (1997) .
Background Reference 04
Lovenberg, T.W., et al., J. Neuroimmunol. 70 (2) :113-122 (1996) .
Other Product Names
Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, IL1R1, IL1R, IL1RA, IL1RT1
Tested Applications
WB, IHC-P
Protein ID
124308
Physical Properties
Liquid

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