IL13 Antibody

• Background :

  This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

• NCBI Gene ID :

  3596

• Swiss Prot :

  P35225

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  A synthetic peptide of human IL13

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Chemokines & Cytokines, Immunology, Innate Immunity

• Purification :

  Affinity purification

• Positive Control :

  NCI-H460

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 24kDa

• Fragment :

  IgG

• Symbol :

  IL13

• NCBI Official Name :

  Interleukin 13

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  IL13, Allergic rhinitis, ALRH, BHR1, Interleukin-13, NC30, p600, IL-13, Interleukin 13

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid