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MAGEA6 Antibody

CAT: 0223-62-154Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-154Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAGEA6 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.
NCBI Gene ID
4105
Swiss Prot
P43360
Accession Number
P43360
Host
Rabbit
Reactivity
Human
Immunogen
This MAGEA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human MAGEA6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
35 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MAGEA6
NCBI Official Name
Melanoma-associated antigen 6
NCBI Organism
Homo sapiens
Background Reference 01
Tatsumi, T., et al., Clin. Cancer Res. 9 (3) :947-954 (2003) .
Background Reference 02
Tatsumi, T., et al., J. Exp. Med. 196 (5) :619-628 (2002) .
Background Reference 03
Imai, Y., et al., Gene 160 (2) :287-290 (1995) .
Background Reference 04
Rogner, U.C., et al., Genomics 29 (3) :725-731 (1995) .
Other Product Names
Melanoma-associated antigen 6, Cancer/testis antigen 16, CT16, MAGE-6 antigen, MAGE3B antigen, MAGEA6, MAGE6
Tested Applications
WB
Protein ID
1170860
Physical Properties
Liquid

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