Products for Research Use Only

EDG2 Antibody

CAT: 0223-62-138Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-138Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The EDG2 integral membrane protein is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.
NCBI Gene ID
1902
Swiss Prot
Q92633
Accession Number
Q92633
Host
Rabbit
Reactivity
Human
Immunogen
This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human EDG2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction, Growth Factors
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LPAR1
NCBI Official Name
Lysophosphatidic acid receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Matsuda, A., et al., Oncogene 22 (21) :3307-3318 (2003) .
Background Reference 02
Van Leeuwen, F.N., et al., J. Biol. Chem. 278 (1) :400-406 (2003) .
Background Reference 03
Shida, D., et al., Cancer Res. 63 (7) :1706-1711 (2003) .
Background Reference 04
Cervera, P., et al., Glia 38 (2) :126-136 (2002) .
Other Product Names
Lysophosphatidic acid receptor 1, LPA receptor 1, LPA-1, Lysophosphatidic acid receptor Edg-2, LPAR1, EDG2, LPA1
Tested Applications
WB
Protein ID
26454626
Physical Properties
Liquid