EDG1 Antibody

• Background :

  EDG1 (Endothelial differentiation gene 1), also called Sphingosine-1-phosphate receptor 1 (S1PR1) is the G-protein coupled receptor for Sphingosine 1-phosphate (S1P) . Via its interaction with S1P, EDG1 is involved in a number of cellular processes. The binding of S1P leads to angiogenesis and tumor cell motility in cancer, and this interaction also participates in the formation of cell-cell adherens junctions. During embryogenesis, it regulates vascularization. EDG1 interacts with the serotonin receptor 5-HT1AR in the central nervous system. It is also a regulator of innate and adaptive immunity by signaling the release of T-cells from lymph nodes.

• NCBI Gene ID :

  1901

• Swiss Prot :

  P21453

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A recombinant protein fragment from the C-terminal portion of human EDG1 was used as the immunogen for this antibody.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology

• Purification :

  Protein A affinity chromatography

• Concentration :

  0.5 mg/mL

• Buffer :

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.

• Fragment :

  IgG

• Symbol :

  S1PR1

• NCBI Official Name :

  Sphingosine-1-phosphate receptor 1

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  S1P1 Antibody: EDG1, S1P1, CD363, ECGF1, EDG-1, CHEDG1, D1S3362, EDG1, Sphingosine 1-phosphate receptor 1, Endothelial differentiation G-protein coupled receptor 1, S1P receptor 1

• Tested Applications :

  WB

• Physical Properties :

  Liquid