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PON2 Antibody

CAT: 0223-62-040Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-040Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PON2 is a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.
NCBI Gene ID
5445
Swiss Prot
Q15165
Accession Number
Q15165
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This PON2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-101 amino acids from the Central region of human PON2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
PON2
NCBI Official Name
Serum paraoxonase/arylesterase 2
NCBI Organism
Homo sapiens
Background Reference 01
Sanghera, D.K., et al. Am. J. Hum. Genet. 62 (1) :36-44 (1998)
Background Reference 02
Hegele, R.A., et al. J. Clin. Endocrinol. Metab. 82 (10) :3373-3377 (1997)
Background Reference 03
Primo-Parmo, S.L., et al. Genomics 33 (3) :498-507 (1996)
Other Product Names
Serum paraoxonase/arylesterase 2, PON 2, Aromatic esterase 2, A-esterase 2, Serum aryldialkylphosphatase 2, PON2
Tested Applications
WB, IHC-P, IF
Protein ID
325511384
Physical Properties
Liquid

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