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TUBB3 Antibody

CAT: 0223-62-035Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-035Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Beta III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells.
NCBI Gene ID
10381
Swiss Prot
Q13509
Accession Number
Q13509
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This TUBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of human TUBB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Monkey, Chicken, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Symbol
TUBB3
NCBI Official Name
Tubulin beta-3 chain
NCBI Organism
Homo sapiens
Background Reference 01
Khan, I.A., et al. Biochemistry 35 (12) :3704-3711 (1996)
Background Reference 02
Khan, I.A., et al. Biochemistry 35 (12) :3704-3711 (1996)
Background Reference 03
Vinores, S.A., et al. Exp. Eye Res. 60 (4) :385-400 (1995)
Other Product Names
Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3, TUBB4
Tested Applications
WB, IHC-P, Flow
Protein ID
20455526
Physical Properties
Liquid

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