RSPO4 Antibody

• Background:

  RSPO4 is a member of the R-spondin family of proteins that share a common domain organization consisting of a signal peptide, cysteine-rich/furin-like domain, thrombospondin domain and a C-terminal basic region. The encoded protein may be involved in activation of Wnt/beta-catenin signaling pathways. Mutations in this gene are associated with anonychia congenital. Alternate splicing results in multiple transcript variants.

• NCBI Gene ID:

  343637

• Swiss Prot:

  Q2I0M5

• Accession Number:

  Q2I0M5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RSPO4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the C-terminal region of human RSPO4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RSPO4

• NCBI Official Name:

  R-spondin-4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bergmann, C., et al. Am. J. Hum. Genet. 79 (6) :1105-1109 (2006)

• Background Reference 02:

  Blaydon, D.C., et al. Nat. Genet. 38 (11) :1245-1247 (2006)

• Background Reference 03:

  Kim, K.A., et al. Cell Cycle 5 (1) :23-26 (2006)

• Other Product Names:

  R-spondin-4, Roof plate-specific spondin-4, hRspo4, RSPO4, C20orf182

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  97189858

• Physical Properties:

  Liquid