Products for Research Use Only
RegisterLogin

RSPO3 Antibody

CAT: 0223-8153-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-8153-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family) /beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis (1,2) . RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development (3,4) .
NCBI Gene ID
84870
Swiss Prot
Q9BXY4
Accession Number
NP_116173
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
RSPO3 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1210 - HEK293 Cell Lysate
Concentration
1 mg/mL
Buffer
RSPO3 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
RSPO3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
RSPO3 antibody is human and mouse reactive. At least three isoforms of RSPO3 are known to exist; this antibody will detect all three.
Symbol
RSPO3
Positive Control 2
Cat. No. 17-010 - HEK293 Cell Slide
NCBI Official Name
R-spondin 3
NCBI Organism
Homo sapiens
Background Reference 01
Chen JZ, Wang S, Tang R, et al. Cloning and identification of a cDNA that encodes a novel human protein with thrombospondin type I repeat domain, hPWTSR. Mol. Biol. Rep. 2002; 29:287-92.
Background Reference 02
Kim KA, Wagle M, Tran K, et al. R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol. Biol. Cell 2008; 19:2588-96.
Background Reference 03
Kazanskaya O, Ohkawara B, Heroult M, et al. The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development 2008; 3655-64.
Background Reference 04
Seshagiri S, Stawiski EW, Durinck S, et al. Recurrent R-spondin fusions in colon cancer. Nature 2012; 488:660-4.
Other Product Names
R-spondin-3, CRISTIN1, PWTSR, THSD2
Tested Applications
ELISA, WB, ICC, IF
Protein ID
18490982
Physical Properties
Liquid

Related Products

CatalogName
8153PRSPO3 Peptide
10-799Rosmantuzumab (RSPO3) - Research Grade Biosimilar
11-542R-Spondin 3 / RSPO3 (22-146) Recombinant Protein
62-016RSPO4 Antibody
61-862RSPO2 Antibody
5171-01mgRSPO1 Antibody
5171-002mgRSPO1 Antibody
5171-01RSPO1 Antibody
5171PRSPO1 Peptide
64-160WAS Antibody

Alternative Products

CatalogName
MBS9611479-01RSPO3 Antibody

Popular Products