RPS3A Antibody

• Background:

  Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S3AE family of ribosomal proteins. It is located in the cytoplasm. Disruption of the gene encoding rat ribosomal protein S3a, also named v-fos transformation effector protein, in v-fos-transformed rat cells results in reversion of the transformed phenotype. Transcript variants utilizing alternative transcription start sites have been described. This gene is co-transcribed with the U73A and U73B small nucleolar RNA genes, which are located in its fourth and third introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

• NCBI Gene ID:

  6189

• Swiss Prot:

  P61247

• Accession Number:

  P61247

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RPS3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the C-terminal region of human RPS3A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Monkey, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  30 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  RPS3A

• NCBI Official Name:

  40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Maggi, L.B. Jr., et al. Mol. Cell. Biol. 28 (23) :7050-7065 (2008)

• Background Reference 02:

  Sugiyama, N., et al. Mol. Cell Proteomics 6 (6) :1103-1109 (2007)

• Background Reference 03:

  Jonson, L., et al. Mol. Cell Proteomics 6 (5) :798-811 (2007)

• Background Reference 04:

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

• Other Product Names:

  40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122}, v-fos transformation effector protein, Fte-1, RPS3A {ECO:0000255|HAMAP-Rule:MF_03122}, FTE1, MFTL

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  47117764

• Physical Properties:

  Liquid