CD63 Antibody

• Background:

  CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.

• NCBI Gene ID:

  967

• Swiss Prot:

  P08962

• Accession Number:

  P08962

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CD63 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-190 amino acids from the C-terminal region of human CD63.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  26 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CD63

• NCBI Official Name:

  CD63 antigen

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Weng, J., et al. J. Virol. 83 (15) :7467-7474 (2009)

• Background Reference 02:

  Kassahn, D., et al. Cell Death Differ. 16 (1) :115-124 (2009)

• Background Reference 03:

  Logozzi, M., et al. PLoS ONE (4), E5219 (2009)

• Other Product Names:

  CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, LAMP-3, Melanoma-associated antigen ME491, OMA81H, Ocular melanoma-associated antigen, Tetraspanin-30, Tspan-30, CD63, CD63, MLA1, TSPAN30

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  116026

• Physical Properties:

  Liquid