CD68 Antibody

CAT: 0223-14-889Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-14-889Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.
NCBI Gene ID
968
Swiss Prot
P34810
Host
Rabbit
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-319 of human CD68 (NP_001242.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
Affinity purification
Positive Control
Mouse fat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 85kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
CD68
Positive Control 2
Mouse skin
Positive Control 3
Rat skin
NCBI Official Name
CD68 molecule
NCBI Organism
Homo sapiens
Other Product Names
Macrosialin, Gp110, CD68, CD68
Tested Applications
WB
Physical Properties
Liquid

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