Tnks 2 Antibody

• Background:

  Tnks 2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Tnks 2 has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.

• NCBI Gene ID:

  80351

• Swiss Prot:

  Q9H2K2

• Accession Number:

  Q9H2K2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Tnks 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1126-1156 amino acids from the C-terminal region of human Tnks 2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  127 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TNKS2

• NCBI Official Name:

  Tankyrase-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Varadi, V., et al. Eur. J. Cancer 45 (17) :3008-3016 (2009)

• Background Reference 02:

  Shebzukhov, Y.V., et al. Cancer Immunol. Immunother. 57 (6) :871-881 (2008)

• Background Reference 03:

  Sidorova, N.N., et al. Biochemistry Mosc. 73 (3) :289-295 (2008)

• Other Product Names:

  Tankyrase-2, TANK2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein, TNKS2, PARP5B, TANK2, TNKL

• Tested Applications:

  WB, Flow

• Protein ID:

  20140805

• Physical Properties:

  Liquid