TNKS Antibody

• Background:

  TNKS may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. It has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.

• NCBI Gene ID:

  8658

• Swiss Prot:

  O95271

• Accession Number:

  NP_003738

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TNKS.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Apoptosis

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  721_B Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store TNKS antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  142 kDa

• Applications Notes:

  TNKS antibody can be used for detection of TNKS by ELISA at 1:312500. TNKS antibody can be used for detection of TNKS by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  TNKS

• NCBI Official Name:

  Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Baynam, G., (2008) Am. J. Med. Genet. A 146A (12), 1565-1570.

• Other Product Names:

  TNKS, PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1, ARTD5, pART5

• Tested Applications:

  ELISA, WB

• Protein ID:

  87239981

• Physical Properties:

  Liquid