ATP4B Antibody

• Background :

  ATP4B belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H (+) and K (+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase.

• NCBI Gene ID :

  496

• Swiss Prot :

  P51164

• Accession Number :

  P51164

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This ATP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human ATP4B.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Obesity, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  33 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  ATP4B

• NCBI Official Name :

  Potassium-transporting ATPase subunit beta

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bab-Dinitz, E., et al. Biochemistry 48 (36) :8684-8691 (2009) Knouff, C.W., et al. Pharmacogenet. Genomics 18 (12) :1051-1057 (2008) Oh, J.H., et al. Mamm. Genome 16 (12) :942-954 (2005)

• Other Product Names :

  Potassium-transporting ATPase subunit beta, Gastric H (+) /K (+) ATPase subunit beta, Proton pump beta chain, ATP4B

• Tested Applications :

  WB, Flow

• Protein ID :

  1703461

• Physical Properties :

  Liquid