ATP5B Antibody

• Background:

  This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c) . This gene encodes the beta subunit of the catalytic core.

• NCBI Gene ID:

  506

• Swiss Prot:

  P06576

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 230-529 of human ATP5B (NP_001677.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SW620

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 57kDa

• Fragment:

  IgG

• Symbol:

  ATP5B

• Positive Control 2:

  BT-474

• Positive Control 3:

  BxPC-3

• Positive Control 4:

  HepG2

• Positive Control 5:

  293T

• Positive Control 6:

  Mouse kidney

• NCBI Official Name:

  ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ATP5B, ATPMB, ATPSB, MGC5231, HEL-S-271

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid