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MAP3K11 Antibody

CAT: 0223-61-820Size: 400 µLDry Ice: NoHazardous: No
CAT#:61-820Size:400 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAP3K11 is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.
NCBI Gene ID
4296
Swiss Prot
Q16584
Accession Number
Q16584
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MAP3K11 antibody is generated from rabbits immunized with MAP3K11 recombinant protein.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
93 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MAP3K11
NCBI Official Name
Mitogen-activated protein kinase kinase kinase 11
NCBI Organism
Homo sapiens
Background Reference 01
Rangasamy, V., et al. Cancer Res. 70 (4) :1731-1740 (2010)
Background Reference 02
Velho, S., et al. Hum. Mol. Genet. 19 (4) :697-706 (2010)
Background Reference 03
Cole, E.T., et al. Biochim. Biophys. Acta 1793 (12) :1811-1818 (2009)
Other Product Names
HGNC:6850
Tested Applications
WB
Protein ID
71153819
Physical Properties
Liquid

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