CD80 Antibody

• Background:

  CD80 is activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells.

• NCBI Gene ID:

  941

• Swiss Prot:

  P33681

• Accession Number:

  P33681

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CD80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the C-terminal region of human CD80.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  33 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CD80

• NCBI Official Name:

  T-lymphocyte activation antigen CD80

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Mosbruger, T.L., et al. J. Infect. Dis. 201 (9) :1371-1380 (2010)

• Background Reference 02:

  Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)

• Background Reference 03:

  Segat, L., et al. J. Gastroenterol. Hepatol. 24 (12) :1840-1846 (2009)

• Other Product Names:

  T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B71, B7, CD80, CD80, CD28LG, CD28LG1, LAB7

• Tested Applications:

  WB, Flow

• Protein ID:

  461606

• Physical Properties:

  Liquid