CD80 Antibody

• Background :

  CD80 is activation antigen B7-1 (formerly referred to as B7) provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 (MIM 186760) and CTLA4 (MIM 123890) ligands of T cells.

• NCBI Gene ID :

  941

• Swiss Prot :

  P33681

• Accession Number :

  P33681

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CD80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the C-terminal region of human CD80.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  33 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CD80

• NCBI Official Name :

  T-lymphocyte activation antigen CD80

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Mosbruger, T.L., et al. J. Infect. Dis. 201 (9) :1371-1380 (2010)

• Background Reference 02 :

  Dubois, P.C., et al. Nat. Genet. 42 (4) :295-302 (2010)

• Background Reference 03 :

  Segat, L., et al. J. Gastroenterol. Hepatol. 24 (12) :1840-1846 (2009)

• Other Product Names :

  T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B71, B7, CD80, CD80, CD28LG, CD28LG1, LAB7

• Tested Applications :

  WB, Flow

• Protein ID :

  461606

• Physical Properties :

  Liquid