PMPCB Antibody

• Background:

  PMPCB is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.

• NCBI Gene ID:

  9512

• Swiss Prot:

  O75439

• Accession Number:

  O75439

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This PMPCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the N-terminal region of human PMPCB.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  54 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PMPCB

• NCBI Official Name:

  Mitochondrial-processing peptidase subunit beta

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Luczynski, W., et al. Neoplasma 56 (5) :428-434 (2009)

• Background Reference 02:

  Schwer, B., et al. J. Cell Biol. 158 (4) :647-657 (2002)

• Background Reference 03:

  Nagao, Y., et al. J. Biol. Chem. 275 (44) :34552-34556 (2000)

• Other Product Names:

  Mitochondrial-processing peptidase subunit beta, Beta-MPP, P-52, PMPCB, MPPB

• Tested Applications:

  WB, IHC-P, Flow

• Physical Properties:

  Liquid