PMPCA Antibody

• Background:

  The protein encoded by this gene is found in the mitochondrion, where it represents the alpha subunit of a proteolytic heterodimer. This heterodimer is responsible for cleaving the transit peptide from nuclear-encoded mitochondrial proteins. Defects in this gene are a cause of spinocerebellar ataxia, autosomal recessive 2.

• NCBI Gene ID:

  23203

• Swiss Prot:

  Q10713

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 456-525 of human PMPCA (NP_055975.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 110kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  PMPCA

• Positive Control 2:

  MCF7

• Positive Control 3:

  Raji

• Positive Control 4:

  HeLa

• NCBI Official Name:

  Mitochondrial-processing peptidase subunit alpha

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, P-55, PMPCA, INPP5E, KIAA0123, MPPA

• Tested Applications:

  WB

• Physical Properties:

  Liquid