ATF1 Antibody

• Background:

  ATF1 binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. ATF1 binds to the Tax-responsive element (TRE) of HTLV-I. ATF1 mediates PKA-induced stimulation of CRE-reporter genes.

• NCBI Gene ID:

  466

• Swiss Prot:

  P18846

• Accession Number:

  P18846

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ATF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-219 amino acids from the C-terminal region of human ATF1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  29 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ATF1

• NCBI Official Name:

  Cyclic AMP-dependent transcription factor ATF-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, W.L., et al. Mod. Pathol. 22 (9) :1201-1209 (2009)

• Background Reference 02:

  Vega, A., et al. Gynecol. Oncol. 112 (1) :210-214 (2009)

• Background Reference 03:

  Zheng, D., et al. Cancer Res. 68 (18) :7650-7660 (2008)

• Other Product Names:

  Cyclic AMP-dependent transcription factor ATF-1, cAMP-dependent transcription factor ATF-1, Activating transcription factor 1, Protein TREB36, ATF1

• Tested Applications:

  WB, Flow

• Protein ID:

  1168542

• Physical Properties:

  Liquid