ATF2 Antibody

• Background:

  ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.

• NCBI Gene ID:

  1386

• Swiss Prot:

  P15336-2

• Accession Number:

  NP_001871

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATF2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Transcription, Cancer

• Purification:

  Antibody is purified by protein A chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store ATF2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  55 kDa

• Applications Notes:

  ATF2 antibody can be used for detection of ATF2 by ELISA at 1:1562500. ATF2 antibody can be used for detection of ATF2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  ATF2

• NCBI Official Name:

  Activating transcription factor 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kravets, A., et al., (2004) J. Biol. Chem. 279 (19), 19916-19923.

• Other Product Names:

  ATF2, HB16, CREB2, TREB7, CREB-2, CRE-BP1

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  22538422

• Physical Properties:

  Liquid